At a Glance

Discipline

  • Biology

Instructional Level

  • College & CEGEP

Course

  • General Biology II

Tasks in Workflow

Social Plane(s)

  • Individual
  • Group
  • Whole Class

Type of Tasks

  • Collecting & seeking information
  • Discussing
  • Solving problems
  • Reviewing & assessing peers
  • Reading
  • Taking a quiz & test

Technical Details

Useful Technologies

  • Clicker System

Time

Single class period (< 90 mins)

Purpose

  • Application & practice

Overview

Gene mutations can be lethal or beneficial to an organism, in this mini case study students will learn the effects mutations can have on phenotypes.

Students will apply what they learned about mutations to decipher the effects it can have on a functional gene (phenotype). They will investigate the outcomes of two mutations; one that leads to a truncated null protein product and one that leads to a functional larger protein.
This mini case study uses the flipped classroom strategy where students will prepare by watching videos, completing assigned readings and taking a quiz before entering the classroom. The instructor ...

Read More +

Gene mutations can be lethal or beneficial to an organism, in this mini case study students will learn the effects mutations can have on phenotypes.

Students will apply what they learned about mutations to decipher the effects it can have on a functional gene (phenotype). They will investigate the outcomes of two mutations; one that leads to a truncated null protein product and one that leads to a functional larger protein.
This mini case study uses the flipped classroom strategy where students will prepare by watching videos, completing assigned readings and taking a quiz before entering the classroom. The instructor can use just in time teaching (JITT) using the quiz results to alter the in-class material.

Read Less -

Instructional Objectives

  • To understand the effects that a mutation can have, whether it can be lethal or beneficial;
  • To understand what the mutation can do to an organism’s phenotype.

Workflow & Materials

Activity Workflow

From "yum" to "yuk": a case in point… mutation

Download

Concepts & Learning Outcomes

Teacher Instruction

Download

Mutations Questions

ConcepTest Questions

Download

Mutations Class Activity

Worksheet

Download

Contributor's Notes

Edward Awad
Edward Awad

Vanier College, Montreal, QC

Benefits

  • This activity helps students in group collaboration. Since the activity uses peer assessment the student’s are more engaged.

Challenges

  • Students get overwhelmed when faced with the multiple choice clicker questions.

Tips

  • This case study is applicable to any gene; therefore the instructor can modify the study to the gene/sequence of their choice;
  • The instructor can use the clicker questions at the beginning of the class.

Applied Strategies

  1. 1
    Case Studies
  2. 2
    Just in Time Teaching (JiTT)
  3. 3
    Peer Assessment
  4. 4
    Peer Instruction
  5. 5
    Flipped Classroom

Feedback

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